Lair Of The Multimedia Guru

November 5, 2017

Genetics history

Maybe a little off topic. But if one looks at DNA sequencing technology, in 2001 sequencing one humans genome cost 100 million USD, in 2015 it was down to slightly above 1000 USD. Today in 2017 you can buy a new DNA sequencer the size of a mobile phone for 1000 USD. Considering this, humankind today basically has the technology to sequence every human genome.
If someone asked me 10 years ago, what one can do about inherited genetic diseases or any thing else genetic. I would have said, wait 200 years till we have molecular-nano-technology and hope WW3 doesn’t happen. But in 2015 Chinese researchers edited human genes in embryos with some success. But still thats basically individual cells in a lab not an adult made of 1013 cells. But in fact similar methods have already been used and demonstrated to also work with individual organs in vivo in adult mice (not sure who did this first or when, but google finds quite a few things). And what i read few days ago according to interim results, non human primates, editing over 20% of liver cells successfully after a single dose and no adverse events with multiple dosing.
Now one wonders a bit, if one extrapolates this, where this tech will be in 5, 10 or 20 years. I think the next decades will be very interesting in this area.

Filed under: Off Topic — Michael @ 0:41

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